Senior Managing Partner & CEO, Flagship Pioneering


President and Chief Executive Officer

Mr. Hinshaw joined Axcella as CEO in May 2018. He is the former Executive Vice President of U.S. Oncology at Novartis Pharmaceuticals Corporation and served 15 years with the organization. Mr. Hinshaw led all aspects of this >$6B organization, leading double-digit launches, including Tasigna®, Gleevec®, and Kymriah®; the integration of the GSK oncology portfolio; innovative medical, commercial, and market access models; and a patient centric focus on education and support programs. He played a key role on the Global Oncology Executive Committee, including leading key strategic programs to maximize the portfolio and develop the pipeline.

Mr. Hinshaw was formerly the Head of the Northern and Central Europe Region for Novartis Oncology where he was responsible for leading all functions across 33 countries. Prior to that role, Mr. Hinshaw was the head of Group Emerging Markets, which included all divisions of Novartis Corporation in 50 countries worldwide.

Prior to his role as EVP, Mr. Hinshaw held a number of lead roles for Novartis including Head of the Hematology Business Franchise, which achieved >20% overall growth each year under Mr. Hinshaw’s leadership. Previously, Mr. Hinshaw was the Global Head of Infectious Disease and Transplantation and Immunology (IDTI) based out of Basel, Switzerland, and was responsible for all functions of the organization, including commercial, development, BD&L, and strategy for the Business Unit. Other positions he has held since joining Novartis in 2003 include: Global Head of Infectious Disease Marketing and IDTI Development and Business Development & Licensing; Business Franchise Head, Infectious Disease; and Head of Infectious Disease Marketing.

Mr. Hinshaw started his career at Schering Plough, where over the course of 12 years he held a series of roles of increasing responsibility in the sales and marketing functions in both primary care and specialty business units. This including market research, new products and in line brand management, and sales positions at the representative, district, regional, and national levels. He also led the U.S. Oncology Unit where he was responsible for sales, marketing and business development.

Mr. Hinshaw holds a B.S. in Molecular Biology from the University of Wisconsin.